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Transient compartmental expression of neurocan in the developing striatum of the rat

✍ Scribed by Igor Charvet; Fiona J. Hemming; Claude Feuerstein; Raymond Saxod

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 580 KB
Volume: 51
Category: Article
ISSN: 0360-4012
DOI: 10.1002/(sici)1097-4547(19980301)51:5<612::aid-jnr8>3.0.co;2-i

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✦ Synopsis

The expression of the chondroitin sulfate proteoglycan neurocan was examined in the developing striatum of the rat and compared with the distribution of dopaminergic terminals. Neurocan immunoreactivity shows a homogeneous pattern in the embryonic striatum. In the postnatal striatum, neurocan was first expressed within the matrix but not the patch compartments, and subsequently within both. These results suggest that chondroitin sulfate proteoglycans are involved in formation of connections between the substantia nigra and striatum.

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