## Abstract Human papillomavirus (HPV) does not induce lysis of infected keratinocytes, and the exact mechanisms of viral escape are not known. As keratinocytes differentiate, the cornified cell envelope (CCE) develops, providing a protective barrier to the host. Our prior studies have identified a
Transglutaminase crosslinking and structural studies of the human small proline rich 3 protein
β Scribed by Steinert, Peter M; Candi, Eleonora; Tarcsa, Edit; Marekov, Lyuben N; Sette, Marco; Paci, Maurizio; Ciani, Barbara; Guerrieri, Pietro; Melino, Gerry
- Book ID
- 110015961
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 570 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1350-9047
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The cell envelope (CE) is a vital structure for barrier function in terminally differentiated dead stratified squamous epithelia. It is assembled by transglutaminase (TGase) cross-linking of several proteins, including hSPR3 in certain specialized epithelia normally subjected to mechanical trauma. B
## Abstract The solid phase synthesis of a 59 amino acid human salivary protein IB7 has been accomplished using Fmoc strategy. Because the protein contains 25 proline, 13 glycine and 9 glutamine residues the coupling time, piperidine delivery and acetic anhydride reaction time were increased. Yield