## Abstract Stimulation of chief cells with carbachol or cholecystokinin (CCK) results in the production of inositol trisphosphate (IP~3~) and diacylglycerol (DAG). Although IP~3~ increases cell calcium concentration, thereby stimulating pepsinogen secretion, the role of DAG and its target, protein
โฆ LIBER โฆ
Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages
โ Scribed by Miyaoka, Youichi; Kadowaki, Yasunori; Ishihara, Shunji; Ose, Takayuki; Fukuhara, Hiroyuki; Kazumori, Hideaki; Takasawa, Shin; Okamoto, Hiroshi; Chiba, Tsutomu; Kinoshita, Yoshikazu
- Book ID
- 110068413
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 476 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0950-9232
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Inflammatory reactions are considered one of the important etiologic factors in the pathogenesis of Alzheimer's disease (AD). Prostaglandins such as PGE 2 and PGA 1 and free radicals are some of the agents released during inflammatory reactions, and they are neurotoxic. The mechanisms of their actio