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Transgenic Mouse: Methods and Protocols

โœ Scribed by Marten H. Hofker (auth.), Marten H. Hofker, Jan van Deursen (eds.)


Publisher
Humana Press
Year
2002
Tongue
English
Leaves
394
Series
Methods in Molecular Biology 209
Category
Library

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โœฆ Subjects


Cell Biology


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Transgenic Mouse Methods and Protocols
โœ Marten H. Hofker (auth.), Marten H. Hofker, Jan van Deursen (eds.) ๐Ÿ“‚ Library ๐Ÿ“… 2011 ๐Ÿ› Humana Press ๐ŸŒ English

<p>The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful. In Transgenic Mouse Methods an

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Genetically very similar to the human species, mice play an important role in biomedical research and have served as experimental models for a wide variety of pathologies, including cancer, cardiovascular diseases, and behavioral disorders. In Transgenic Mouse Methods and Protocols, Marten Hofker an

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<p><p>This volume provides readers with a historical foundation in standard techniques and a comprehensive update on the latest methods used in making gene-modified mice. The chapters in this book cover topics such as pronuclear microinjection in one-cell embryos; embryo transfer surgery; nuclear tr

Transgenic Mouse: Methods and Protocols
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Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularlyfor generating mouse models that will enable us to better understand gene function. Described in step-by-step detail by highly experienced investigat