Skeletal development in transgenic mice
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B. Kerry Maddox; Silvio Garofalo; Chad Smith; Douglas R. Keene; William A. Horto
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Article
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1997
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John Wiley and Sons
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English
⚖ 407 KB
Skeletal development of transgenic mice with a type II collagen mutation was analyzed and compared with wild-type littermates. The single base substitution in Col2a1 resulted in a glycine to serine mutation within the helical domain and corresponded to one previously identified in a patient with the