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Transgenic expression ofCECR1adenosine deaminase in mice results in abnormal development of heart and kidney

✍ Scribed by Ali M. Riazi; Glen Van Arsdell; Manuel Buchwald

Book ID
106550182
Publisher
Springer Netherlands
Year
2005
Tongue
English
Weight
261 KB
Volume
14
Category
Article
ISSN
0962-8819

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## Abstract Myostatin, a member of the TGF‐β family, negatively regulates skeletal muscle development. Depression of myostatin activity leads to increased muscle growth and carcass lean yield. In an attempt to down‐regulate myostatin, transgenic mice were produced with a ribozyme‐based construct or