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Attenuation of retinal vascular development and neovascularization in transgenic mice over-expressing thrombospondin-1 in the lens

✍ Scribed by Zhifeng Wu; Shoujian Wang; Christine M. Sorenson; Nader Sheibani


Book ID
102817665
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
617 KB
Volume
235
Category
Article
ISSN
1058-8388

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## Abstract Summary: Deletion of the tyrosinase locus control region (LCR) in transgenic mice results in variegated expression in the skin. Here we investigate the pigmentation pattern of other tissues that express tyrosinase: iris, choroid, and retina in the same animals. A mosaic distribution of