Transfusion of autologous cytokine-induced killer cells inhibits viral replication in patients with chronic hepatitis B virus infection
β Scribed by Ming Shi; Junliang Fu; Feng Shi; Bin Zhang; Zirong Tang; Lei Jin; Zhenping Fan; Zheng Zhang; Liming Chen; Huifeng Wang; George K.K. Lau; Fu-Sheng Wang
- Book ID
- 113540764
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 653 KB
- Volume
- 132
- Category
- Article
- ISSN
- 1090-2341
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IFN-a and lamivudine, were treated with 16 weeks of 10 megaunits PBMC, peripheral blood mononuclear cell; SI, stimulation index; ALT, alanine transami-of recombinant IFN-a 2b (Intron-A; Schering-Plough, Welwyn Garnase. den City, England) subcutaneously three times a week and 100 mg From the Institu
Previous studies demonstrated that peripheral blood lymphocytes are cytotoxic to autologous hepatocytes in patients with chronic hepatitis B virus infection. We examined whether cytotoxicity is specifically directed against hepatocytes expressing HBsAg or HBcAg. Viral antigens were detected by immun