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Transforming growth factor–β3 is required for secondary palate fusion

✍ Scribed by Proetzel, Gabriele; Pawlowski, Sharon A.; Wiles, Michael V.; Yin, Moying; Boivin, Gregory P.; Howles, Philip N.; Ding, Jixang; Ferguson, Mark W. J.; Doetschman, Thomas


Book ID
109918885
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
836 KB
Volume
11
Category
Article
ISSN
1061-4036

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Transforming growth factor ␤ (TGF-␤) is a potent inhibitor of hepatocyte proliferation in vitro and is suggested to be a key negative regulator of liver growth. To directly address the role of TGF-␤ signaling in liver regeneration in vivo, the TGF-␤ type II receptor gene (Tgfbr2) was selectively del