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PI-3 kinase activity is required for epithelial-mesenchymal transformation during palate fusion

✍ Scribed by Pei Kang; Kathy K.H. Svoboda


Book ID
102154466
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
449 KB
Volume
225
Category
Article
ISSN
1058-8388

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Overexpression of the growth factor receptor ErbB-2/Her2/ Neu has been implicated in the development of non-small-cell lung cancer. We have reported that the transformation of human lung epithelial cells by c-erbB-2 also requires an active ErbB-1 (EGF receptor) and the autocrine production of its li