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Transforming growth factor-β (TGF-β) type I and type II receptors are both required for TGF-β-mediated extracellular matrix production in lung fibroblasts

✍ Scribed by Yun Zhao


Book ID
117464158
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
269 KB
Volume
150
Category
Article
ISSN
0303-7207

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Transforming growth factor-b (TGF-b1) is a potent negative regulator of cell growth that transduces signals through interactions with type I and II receptors. Abnormal expression and mutational alterations of these receptors have been observed in several human malignancies. In this study, we investi