Transforming growth factor β regulates cell–cell adhesion through extracellular matrix remodeling and activation of focal adhesion kinase in human colon carcinoma Moser cells
✍ Scribed by Wang, Hongmei; Radjendirane, Venugopal; Wary, Kishore K; Chakrabarty, Subhas
- Book ID
- 110068772
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 137 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0950-9232
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## Abstract A hallmark of transforming growth factorβ (TGFβ) action is the induction of the synthesis and secretion of extracellular‐matrix adhesion molecules and induction of the cell‐surface expression of integrin receptors for these molecules (termed extracellular‐matrix remodeling). The signal
## I c x a s 770 3 0 Alterations in the binding of transforming growth factor-p (TGF-P) to the MOSCR human colon carcinoma cell line caused by N,N-dirnethylformamide (DMF) or extrac-rllular matrix (ECM) werc examined. LIMF induced a morc dif'fercntiated phenntypc in the MOStK cells and resulted in