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Transforming growth factor-β: Recent advances on its role in immune tolerance

✍ Scribed by Martin A. Kriegel; Ming O. Li; Shomyseh Sanjabi; Yisong Y. Wan; Richard A. Flavell


Book ID
107553867
Publisher
Springer
Year
2006
Tongue
English
Weight
171 KB
Volume
8
Category
Article
ISSN
1523-3774

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Transforming growth factor-b (TGF-b) is known to mediate pleiotropic functions both inside and outside the immune system. Recent progress in this field underlines the role of TGF-b in regulatory T (Treg) cells, where it participates in both suppression and differentiation. In addition, recent inform