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Transforming Growth Factor-β Induces Apoptosis in Activated Murine T Cells through the Activation of Caspase 1-like Protease

✍ Scribed by Eun Joo Chung; Sang Hoon Choi; Yhong-Hee Shim; Yung-Jue Bang; Kuy Chung Hur; Chul Woo Kim


Book ID
112240316
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
255 KB
Volume
204
Category
Article
ISSN
0008-8749

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Transforming growth factor-beta1 (TGF-beta1) arrests growth and/or stimulates apoptosis of a variety of cells. The biochemical pathways involved in the apoptotic processes, however, remain poorly defined. TGF-beta1 induces DNA fragmentation together with morphological changes, which are characterist