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Transforming growth factor-β in in vivo resistance

✍ Scribed by B. A. Teicher; Sylvia A. Holden; Gulshan Ara; Guan Chen

Publisher
Springer
Year
1996
Tongue
English
Weight
388 KB
Volume
37
Category
Article
ISSN
0344-5704

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Transforming growth factor-beta (TGF-beta) has been implicated in the in vivo resistance of the EMT-6/CTX and EMT-6/ CDDP murine mammary tumors. Both of these tumors have a higher number of intratumoral vessels than the EMT-6/ parent tumor. Animals bearing the resistant tumors have higher plasma lev