𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Transforming Growth Factor-α Precursors in Human Colon Carcinoma Cells

✍ Scribed by Mònica Asbert; Beatriz Montaner; Ricardo Pérez-Tomás

Book ID
110292773
Publisher
Springer US
Year
2001
Tongue
English
Weight
520 KB
Volume
46
Category
Article
ISSN
0163-2116

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differential role of transforming growth
Differential role of transforming growth factor-α in two human colon-carcinoma cell lines
✍ Linda F. Watkins; Alan E. Levine 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 702 KB

Antibodies to epidermal-growth-factor receptor (EGF) and transforming growth factor-a (TGVa) were used to determine the role of endogenous TGF-a in the growth of 2 human colon-carcinoma cell lines. Both the GEO and HCT I 16 coloncarcinoma cell lines secrete similar levels of TGF-a and have similar n

Proliferation of human colon cancer cell
Proliferation of human colon cancer cells: Role of epidermal growth factor and transforming growth factorα
✍ Shuang Huang; Jose M. Trujillo; Subhas Chakrabarty 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 773 KB

## Abstract Human colon cancer cells produce and secrete a variety of polypeptide growth factors. The functional role of these growth factors, however, is poorly understood. Though the secretion of epidermal growth factor (EGF)‐like activity and EGF‐related molecules by human colon cancer cells in

Pro-transforming growth factor-alpha pro
Pro-transforming growth factor-alpha processing in human colon carcinoma cells: Role of protein kinase C
✍ Gadiraju Ramesh; Alan E. Levine 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 842 KB

The human colon cancer cell lines HCT I I 6 (poorly differentiated) and GEO (well differentiated) express the mitogenic peptide transforming growth factor alpha (TGF-a). The secretion of TGF-awas enhanced by phorbol 12-myristate 13-acetate (PMA), indicating the possible role of protein kinase C (PKC

Increased transforming growth factor-α l
Increased transforming growth factor-α levels in human colon carcinoma cell lines over-expressing protein kinase C
✍ Padma Maruvada; Alan E. Levine 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 154 KB 👁 1 views

Transforming growth factor-␣ (TGF-␣) is synthesized as a membrane-bound precursor protein, pro-TGF-␣, that is converted to a soluble form by 2 endoproteolytic cleavages. Several factors have been implicated in the regulation of the second rate-limiting step, including protein kinase C (PKC). Earlier