Transformations of the Picrotoxanes: The Synthesis of Corianin and Structural Analogues from Picrotoxinin. -The neurochemically active sesquiterpene corianin (I) and some related compounds are prepared to study structure-activity relationships. -(KRISCHE, M.
Transformations of the picrotoxanes: The synthesis of corianin and structural analogues from picrotoxinin
โ Scribed by Michael J. Krische; Barry M. Trost
- Book ID
- 104208618
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 586 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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๐ SIMILAR VOLUMES
The Palladium-Catalyzed Enyne Cycloisomerization Reaction in a General Approach to the Asymmetric Syntheses of the Picrotoxane Sesquiterpenes. Part 1. First-Generation Total Synthesis of Corianin (V) and Formal Syntheses of Picrotoxinin (VIa) and Picrotin (VIb).
THE structure (Ia) proposed for picrotoxinin (C15H1606) by Conroy lp2 and supported by his conformational analysis has now been confirmed by the crystal structure analysis of a bromo derivative (C15H1506Br) using the methods of X-ray diffraction. Crystals of a-bromopicrotoxinin, for which Ib IIb