Transformation of azido-group to n-(t-butoxycarbonyl)amino group under mild conditions via staudinger reaction
โ Scribed by Carlos A.M. Afonso
- Book ID
- 103409970
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 252 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Studies on the Transformation of Azido-Group to N-(t-Butoxycarbonyl)amino Group via Staudinger Reaction. -A simple and convenient method for the direct conversion of primary azides into N-Boc-amines [cf. (III), (V), (VII)] via iminophosphorane intermediates is described. The formation of symmetrica
## Abstract An efficient method of peptide thioester synthesis is described. The reaction is based on an __N__โ4,5โdimethoxyโ2โmercaptobenzyl (Dmmb) auxiliaryโassisted __N__โ__S__ acyl shift reaction after assembling a peptide chain by Fmocโsolid phase peptide synthesis. The Dmmbโassisted __N__โ__S