## Abstract A one‐step ‘ring switching’ transformation of (__S__)‐3‐[(dimethylamino)methylidene]‐5‐(methoxycarbonyl)tetrahydrofuran‐2‐one (**4**) with 2‐pyridineacetic acid derivatives (**5–7**) and 2‐aminopyridines (**8, 9**) afforded the corresponding 3‐(4‐oxo‐4__H__‐quinolizinyl‐3)‐ **(15–17)**
Transformation of alkyl esters of 4-oxo-3-phenylthioalkanoic acids into substituted 4-phenylthio-2(5H)-furanones and 3-phenylthiofurans
✍ Scribed by O. G. Kulinkovich; I. G. Tishchenko; Yu. N. Romashin
- Publisher
- Springer US
- Year
- 1988
- Tongue
- English
- Weight
- 319 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0009-3122
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📜 SIMILAR VOLUMES
Easily available 3,4-dibromo-2(5H)-furanone undergoes a regioselective cross-coupling reaction with alkylboronic acids in the presence of catalytic amounts of PdCl2(MeCN)2 and AsPh3 and a large molar excess of Ag2O to provide the corresponding 4-alkyl-3-bromo-2(5H)-furanones in satisfactory yields.
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## Abstract 3,4‐Dichloro‐2(5__H__)‐furanone, which has been prepared efficiently from mucochloric acid, has been transformed selectively into 4‐aryl‐3‐chloro‐2(5__H__)‐furanones either by Suzuki‐ or Stille‐type reactions. These monochloro derivatives have been used as precursors either to (__Z__)‐4