𝔖 Bobbio Scriptorium
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Transformation of 7,8-dihydrocodeinone to 7,8-dihydroisocodeine by Aureobasidium pullulans

✍ Scribed by J. Fuska; A. Khandlová; B. Proksa; A. Fusková


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
202 KB
Volume
8
Category
Article
ISSN
0138-4988

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✦ Synopsis


Anireobasidiuni pulldnns reduced stereospecifically 7,8-dihyclrocodeinone to 7,s-dihydroisocodeine. Activity of the culture was inhibited by some substances present in the malt extract.


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A rapid, simple, and inexpensive thin-layer chromatography method was developed to follow and to quantify enzymatic reactions of the title enzymes without need of a microbiological test system. The method was used to measure the kinetics of product formation by the folate-synthesizing enzymes 7,8-di