ChemInform Abstract: Enantioselective Synthesis of (7R,8R,8aR)- and (7S,8S,8aS)-7-Hydroxy-8-indolizidinemethanol by 1,3-Dipolar Cycloaddition of 1-Pyrroline N-Oxide to Chiral Pentenoates.
β Scribed by Franca Maria Cordero; Cristina Faggi; Francesco De Sarlo; Alberto Brandi
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 33 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Use of an Iodonium Ylide in the Synthesis of p-Nitrobenzyl (6R,7S) 3-Hydroxy-8-oxo-7-phenoxyacetamido-1-azabicyclo [4.2.0]octa-2-ene-2-carboxylate. -The title compound (IV), a key intermediate in the synthesis of carbacephalosporins, is prepared by Rh(II)-catalyzed cyclization of the iodonium ylide