Conversion of 4,6-disubstituted pyrimidi
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H. C. van der Plas; H. Jongejan
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Article
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2010
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Elsevier Science
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English
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## Abstract 4,6โDiethoxyโ, 4โethoxyโ6โhydrazinoโ, 4,6โdichloroโ, 4,6โdi(methylthio)โand 4,6โdihydrazinopyrimidine react with aqueous hydrazine at 210ยฐ to give 3โmethylโ1,2,4โtriazole. Evidence is presented that in this unprecedented ring contraction reaction the C(2)โN(3 or 1)โC(4 or 6)โC(5) fragme