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Transformation by Oncogenic Ras Expands the Early Genomic Response to Transforming Growth Factor β in Intestinal Epithelial Cells

✍ Scribed by Allen, Carl E.; Du, Jianguo; Jiang, Bo; Huang, Qin; Yakovich, Adam J; Barnard, John A.

Book ID
122327208
Publisher
Neoplasia Press
Year
2008
Tongue
English
Weight
443 KB
Volume
10
Category
Article
ISSN
1522-8002

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## Abstract Spontaneously immortalized human mammary epithelial cells MCF‐IOA were transfected with an activated c‐Ha‐ras oncogene. Transfected cells (MCF‐IOT) acquire a malignant pheno‐type, as already reported. Studies of l‐2′‐deoxyuridine incorporation in cultures given graded doses of hydrocort