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Transferrin (Tf) polymorphism: An analysis by isoelectric focusing

✍ Scribed by Ismail M. Sebetan; Shigemi Oshida; Suguru Akaishi

Book ID
113369098
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
662 KB
Volume
19
Category
Article
ISSN
0379-0738

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A sample of 450 sera from unrelated individuals from Southern Germany was examined by isoelectric focusing on polyacrylamide gels. Three common subtypes, TfC1, C2-1, and C2, were differentiated. In addition, the rare variants TfB1, B1-2, B2, D1, D1-2, D2, and D3 were observed. The frequencies of the

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TransferrinC (TfC) subtypes were determined by isoelectric focusing (PAGIF) on samples from 90 carriers of the TFB and TfD alleles. In all cases of CB and CD heterozygotes only one of the two common subtypes of the TfC allele, TfC1 or TfC2, was observed. This is considered strong support for the hyp

Group-specific component (Gc) and transf
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✍ Bernadette Hoste πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 237 KB

Simultaneous subtyping of Gc and TfC by isoelectric focusing allows us to compute the following gene frequencies for the Belgian population: Gc1S = 0.543 Gc1F = 0.167 Gc2 = 0.290 TfC1 = 0.784 TfC2 = 0.206 TfB = 0.007 TfD = 0.003. The Gc bands were precipitated by sulfosalicylic acid instead of by im