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Transfer of specificity by murine α and β T-cell receptor genes

✍ Scribed by DembiĆ, Zlatko; Haas, Werner; Weiss, Siegfried; McCubrey, James; Kiefer, Hansruedi; von Boehmer, Harald; Steinmetz, Michael


Book ID
109743087
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
738 KB
Volume
320
Category
Article
ISSN
0028-0836

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In B cells the loci encoding immunoglobulin chains usually show allelic exclusion; a given B cell transcribes and translates only one productively rearranged allele of the heavy and light chain loci. This ensures that each B cell expresses only one antigen receptor. The loci encoding T-cell receptor