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Transesterification of α-Substituted Esters Mediated by Potassium Carbonate.

✍ Scribed by Dominik Janczewski; Ludwik Synoradzki; Marek Wlostowski


Book ID
101943193
Publisher
John Wiley and Sons
Year
2003
Weight
12 KB
Volume
34
Category
Article
ISSN
0931-7597

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✍ Scott Eagon; Nicholas Ball-Jones; Dustin Haddenham; Jaime Saavedra; Cassandra De 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 264 KB

A facile and mild reduction procedure is reported for the preparation of chiral secondary alcohols prepared from a-substituted ketones using sodium borohydride and the chiral boronate ester (L)-TarB-NO 2 . Direct reduction of substituted ketones bearing Lewis basic heteroatoms generally provided sec