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Transduction of chemostimuli by the type I carotid body cell

✍ Scribed by C. Peers; K. J. Buckler

Publisher
Springer
Year
1995
Tongue
English
Weight
825 KB
Volume
144
Category
Article
ISSN
0022-2631

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✦ Synopsis

The postulated mechanisms for hypoxic and acidic chemotransduction by type I cells that we have described here are summarized in the diagrams of Fig. 4. Most if not all of these require more complete evaluation and, as we have described, there are obvious points of contention that need to be resolved. Nevertheless, it is apparent that studies of isolated type I cell preparations carried out over the last six years have provided significant advancements in our understanding of chemotransduction in the type I cell. Only when the functioning of these cells has been fully described can we hope to understand the mechanisms underlying the responses of the intact organ to chemostimuli.

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