We have analyzed the ability of a recombinant replication-defective adenovirus to transfer the thymidine kinase gene of herpes simplex virus (HSV-tk) into hepatocellular carcinoma (HCC) cells to confer sensitivity to ganciclovir. Three HCC cell lines (Hep3B, PLC/PRF/5, and HepG2) were efficiently in
✦ LIBER ✦
Transduction efficacy, antitumoral effect, and toxicity of adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir therapy of hepatocellular carcinoma: The woodchuck animal model
✍ Scribed by Bilbao, Roberto; Gérolami, René; Bralet, Marie-Pierre; Qian, Cheng; Tran, Phuong Lan; Tennant, Bud; Prieto, Jesus; Bréchot, Christian
- Book ID
- 110017708
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 741 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0929-1903
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