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Transcriptional regulation of the myosin heavy chain IIB gene in inactive rat soleus

✍ Scribed by Gary E. McCall; Fadia Haddad; Roland R. Roy; Hui Zhong; V. Reggie Edgerton; Kenneth M. Baldwin


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
140 KB
Volume
40
Category
Article
ISSN
0148-639X

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Myosin heavy chain (MHC) and fiber size properties of the adult rat soleus were determined after 4-60 days of complete inactivity, i.e., lumbar spinal cord isolation. Soleus atrophy was rapid and progressive, i.e., 25% and 64% decrease in weight and 33% and 75% decrease in fiber size after 4 and 60

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## Abstract Myosin heavy chain (MHC) mRNA and protein profiles in adult rat soleus and adductor longus were determined after 4, 8, 15, 30, 60, and 90 days of spinal cord isolation (SI). SI results in complete neuromuscular inactivity while leaving the motoneuron–muscle fiber connections intact. Fro

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