Direct interaction between transcription factors may provide a mechanism for the regulatory function of these proteins on transcription of the responsive genes. These interactions may be facilitated if the target DNA sequences for the participant regulatory proteins are overlapped or positioned in c
Transcriptional regulation of IER3IP1 gene by tumor necrosis factor-α and Sp family proteins
✍ Scribed by Wai Han Yiu; Tsz Lun Yeung; Jodie Wing Ming Poon; Stephen Kwok Wing Tsui; Kwok Pui Fung; Mary Miu Yee Waye
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 189 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1613
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## Abstract ## Objective To investigate the role of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in spondylarthropathy (SpA) synovitis. ## Methods Paired samples of synovial biopsy tissue as well as serum and synovial fluid (SF) from 41 patients wit