Transcriptional regulation of hepatic stellate cells
โ Scribed by Jelena Mann; Derek A. Mann
- Book ID
- 113418340
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 761 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0169-409X
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Abbreviations: HSC, hepatic stellate cells; โฃ-SMA, โฃ smooth muscle actin; PDGF, platelet-derived growth factor; PPARโฅ, peroxisome proliferator-activated receptor โฅ; 9-cisRA, 9-cis retinoic acid; RXR, retinoic X receptor; 15d-PGJ 2 , 15-deoxy-โฌ 12,14 prostaglandin J 2 ; [ 3 H]TdR, [methyl-3 H]thymidi
## Abstract ## Background Dominantโnegative transforming growth factor ฮฒ type II receptor (TฮฒRIIฮcyt) is a protein that blocks transforming growth factor (TGFโฮฒ) signaling. Because the consequences of blocking TGFโฮฒ have not been completely elucidated in liver fibrosis, we analysed the effects of