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Transcriptional Regulation of AKT Activation by E2F

โœ Scribed by Marie Chaussepied; Doron Ginsberg


Book ID
116753706
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
281 KB
Volume
16
Category
Article
ISSN
1097-2765

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Cellular transcription factor E2F1 is thought to regulate the expression of genes important for cell cycle progression and cell proliferation. Deregulated E2F1 expression induces S-phase entry in quiescent cells and inhibits myogenic differentiation. We show here that E2F1 inhibits the activation of