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Transcriptional regulation by p53: one protein, many possibilities

โœ Scribed by Laptenko, O; Prives, C

Book ID
110017216
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
269 KB
Volume
13
Category
Article
ISSN
1350-9047

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## Background The use of integrating viral vectors in Gene therapy clinical trials has pointed out the problem of the deleterous effect of the integration of the ectopic gene to the cellular genome and the safety of this strategy. We proposed here a way to induce the death of gene modified cells up