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Transcriptional networks in developing and mature B cells

โœ Scribed by Matthias, Patrick; Rolink, Antonius G.

Book ID
109954976
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
692 KB
Volume
5
Category
Article
ISSN
1474-1741

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Transcription factors including PU.1, E2A and early B cell factor (EBF) are essential for the earliest stages of B lymphocyte development. Recent advances suggest that, although PU.1 initiates events leading to B lymphopoiesis, it might be dispensable at later stages of development. E2A proteins are