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Transcriptional modulation of HIV-1C LTR promoter

✍ Scribed by Anand Singh,Pradeep Ramalingam,Jayanth Kumar Palanichamy…


Book ID
115009115
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
130 KB
Volume
12
Category
Article
ISSN
1471-2334

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## Abstract In human immunodeficiency virus type 1 (HIV‐1) latently infected cells, NF‐kappaB (NF‐κB) plays a critical role in the transcriptional induction of the HIV‐1 promoter. The __trans__‐activating ability of NF‐κB can be modified by another nuclear factor C/EBPβ that can physically bind to