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Transcriptional inhibition of the human papilloma virus reactivates tumor suppressor p53 in cervical carcinoma cells

โœ Scribed by D. V. Kochetkov; G. V. Ilyinskaya; P. G. Komarov; E. Strom; L. S. Agapova; A. V. Ivanov; A. V. Budanov; E. I. Frolova; P. M. Chumakov

Book ID
110174454
Publisher
SP MAIK Nauka/Interperiodica
Year
2007
Tongue
English
Weight
288 KB
Volume
41
Category
Article
ISSN
0026-8933

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โœ William E. Pierceall; Tapas Mukhopadhyay; Leonard H. Goldberg; Honnavara N. Anan ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 528 KB

In this study, we analyzed 10 human squamous cell carcinomas (SCCs) for alterations in the p53 tumor suppressor gene in exons 4 through 9 by single-strand conformation polymorphism (SSCP) analysis. We found that 2 of 10 SCCs displayed unusual SSCP alleles at exon 7 of the p53 gene. Subsequent clonin