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Transcriptional Induction of Metallothionein-I and -II Genes in the Livers of Cu,Zn-Superoxide Dismutase Knockout Mice

✍ Scribed by Kalpana Ghoshal; Sarmila Majumder; Zhiling Li; Tamy M. Bray; Samson T. Jacob

Book ID
115584659
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
245 KB
Volume
264
Category
Article
ISSN
0006-291X

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Liver and lung metallothionein (MT) levels were increased by endotoxin. The administration of superoxide dismutase (SOD) or allopurinol (ALLO) before (30-60 min) or after (24-32 h) the endotoxin treatment either increased or did not affect the effect of endotoxin on MT levels, depending on the parti