Transcriptional control of the testis-specific histone H1t gene
β Scribed by S.R Grimes; D.C Wilkerson; K.R Noss; S.A Wolfe
- Book ID
- 117521215
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 194 KB
- Volume
- 304
- Category
- Article
- ISSN
- 0378-1119
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The testis-specific histone H1t is synthesized during spermatogenesis exclusively in late pachytene primary spermatocytes. Transcription of the H1t gene is repressed in every tissue except testis. Within the testis, transcription is repressed during development before the spermatocyte stage and in l
The rat testis-specific linker histone H1t gene is transcribed in pachytene primary spermatocytes during spermatogenesis. Our previous work using transgenic mice demonstrated that spermatocyte-specific transcription of the H1t gene is dependent upon a proximal promoter element designated the TE elem
The testis-specific linker histone H1t gene is transcribed exclusively in mid to late pachytene primary spermatocytes. Tissue specific expression of the gene is mediated in large part through elements located within the proximal promoter. Previous work in transgenic animals showed that a unique 40 b
## Abstract Transcription of the mammalian testisβspecific linker histone __H1t__ gene occurs only in pachytene primary spermatocytes during spermatogenesis. Studies of the wild type (Wt) and mutant H1t promoters in transgenic mice show that transcription of the __H1t__ gene is dependent upon the T