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Transcriptional and translational control of TNF-α gene expression in human monocytes by major histocompatibility complex class II ligands

✍ Scribed by Enric Espel; Jose A. Garcia-Sanz; Vincent Aubert; Véronique Menoud; Peter Sperisen; Neus Fernández; François Spertini


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
884 KB
Volume
26
Category
Article
ISSN
0014-2980

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## Abstract Tumour necrosis factor alpha (TNF) mRNA is detected in the macrophage infiltrate surrounding the tumour, but the cellular/ molecular interactions leading to TNF gene expression in macrophages are unknown. The __in vitro__ system in which human blood monocytes are stimulated with human c