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Divergent evolution in the mechanisms controlling major histocompatibility complex class II gene transcription in mouse and human

✍ Scribed by Andrea De Lerma Barbaro; Gildas Rigaud; Silvia Sartoris; Morena Nicolis; Tiziana Cestari; Roberto S. Accolla


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
458 KB
Volume
26
Category
Article
ISSN
0014-2980

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## Communicated by Henrik Dahl MHC class II deficiency is a severe primary immunodeficiency characterised by the absence of major histocompatibility complex class II (MHC-II) gene expression. It is genetically heterogeneous and can result from defects in at least four different trans-acting regula