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Transcriptional Activity of the Promoter Region of Rat Frizzled-Related Protein Gene

✍ Scribed by Judy Wai Ping Yam; Koon Wing Chan; Vincent Kam Wai Wong; W.L. Wendy Hsiao


Book ID
115588408
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
183 KB
Volume
286
Category
Article
ISSN
0006-291X

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## Abstract ## BACKGROUND. The secreted frizzled‐related protein 1 gene (__SFRP1__) encodes a Wnt/β‐catenin signaling antagonist and frequently is inactivated by promoter methylation in many tumors. However, the role of __SFRP1__ in hepatocellular carcinoma (HCC) is not clear. Therefore, the autho