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Transcriptional regulation of the promoter of the rat frizzled related protein gene by CREB

✍ Scribed by Yam, Judy Wai Ping; Chan, Koon Wing; Hsiao, W L Wendy

Book ID
110067593
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
314 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract ## BACKGROUND. The secreted frizzled‐related protein 1 gene (__SFRP1__) encodes a Wnt/β‐catenin signaling antagonist and frequently is inactivated by promoter methylation in many tumors. However, the role of __SFRP1__ in hepatocellular carcinoma (HCC) is not clear. Therefore, the autho