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Transcriptional activity of megakaryoblastic leukemia 1 (MKL1) is repressed by SUMO modification

✍ Scribed by Koji Nakagawa; Noboru Kuzumaki

Book ID
108731790
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
768 KB
Volume
10
Category
Article
ISSN
1356-9597

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## Abstract Small ubiquitin‐like modifiers (SUMO) are post‐translational modifiers that regulate target protein activity in diverse ways. The most common group of SUMO substrates is transcription factors, whose transcriptional activity can be altered positively or negatively as a result of SUMOylat