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Transcriptional activation of the urokinase receptor gene by endothelin-1

✍ Scribed by Ci-Jiang He; Geneviève Nguyen; Xiao Mei Li; Marie-Noëlle Peraldi; Colette Adida; Eric Rondeau; Jean-Daniel Sraer

Book ID
117055765
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
563 KB
Volume
186
Category
Article
ISSN
0006-291X

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## Abstract Treatment with 10^−8^ m 1,25‐dihydroxyvitamin D~3~ for 24 h causes transcriptional activation of the human insulin receptor gene in U‐937 human promonocytic cells. The activation seems to potentiate the response to insulin in terms of glucose oxidation. Wortmannin, a phosphatidylinosito