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Transcriptional activation of the Drosophila ecdysone receptor by insect and plant ecdysteroids

✍ Scribed by Keith D Baker; James T Warren; Carl S Thummel; Lawrence I Gilbert; David J Mangelsdorf


Book ID
117672896
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
384 KB
Volume
30
Category
Article
ISSN
0965-1748

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## Abstract Treatment with 10^βˆ’8^ m 1,25‐dihydroxyvitamin D~3~ for 24 h causes transcriptional activation of the human insulin receptor gene in U‐937 human promonocytic cells. The activation seems to potentiate the response to insulin in terms of glucose oxidation. Wortmannin, a phosphatidylinosito