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Transcription suppression of SARI (suppressor of AP-1, regulated by IFN) by BCR-ABL in human leukemia cells

✍ Scribed by Qing Huang; Yan Yang; Xiaoqing Li; Shiang Huang


Book ID
107693980
Publisher
S. Karger AG
Year
2011
Tongue
English
Weight
287 KB
Volume
32
Category
Article
ISSN
1010-4283

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## Abstract A series of pyrazolo[3,4‐d]pyrimidines, previously found to be Src inhibitors, was tested for their ability to inhibit proliferation of three Bcr‐Abl‐positive human leukemia cell lines (K‐562, KU‐812, and MEG‐01), on the basis of the experimental evidence that various Src inhibitors are