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Transcription of the vascular endothelial growth factor receptor-3 (VEGFR3) gene is regulated by the zinc finger proteins Sp1 and Sp3 and is under epigenetic control

✍ Scribed by Hertel, Johannes; Hirche, Christoph; Wissmann, Christoph; Ebert, Matthias P.; Höcker, Michael

Book ID
125385226
Publisher
Springer Netherlands
Year
2014
Tongue
English
Weight
933 KB
Volume
37
Category
Article
ISSN
1570-5870

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✍ Alia Al-Sarraj; Regina M. Day; Gerald Thiel 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB

## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same