𝔖 Bobbio Scriptorium
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Transcription factors p53 and HIF-1α as targets of nitric oxide

✍ Scribed by Bernhard Brüne; Andreas von Knethen; Katrin B. Sandau


Book ID
114283582
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
204 KB
Volume
13
Category
Article
ISSN
0898-6568

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## Abstract Poly(ADP‐ribose) polymerase‐1 (PARP‐1) is a nuclear protein that, once activated by genotoxic agents, modulates the activity of several nuclear proteins including itself. Previous studies have established that PARP‐1 inhibition may provide benefit in the treatment of different diseases,