## Abstract The Xโbox binding protein RFX4 is highly expressed in testis in contrast with other tissues, but its function there is unknown. Another family member abundant in testis, RFX2, has been shown to bind to the XโBox elements in the promoter of the testis specific histone H1t, which is expre
Transcription factor-binding sites responsible for NO-dependent repression of the histone H2B promoter
โ Scribed by E. V. Pankratova; E. A. Manuylova; A. G. Stepchenko
- Book ID
- 110174680
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2009
- Tongue
- English
- Weight
- 210 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0026-8933
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## Abstract Transcription of the mammalian testisโspecific linker histone __H1t__ gene occurs only in pachytene primary spermatocytes during spermatogenesis. Studies of the wild type (Wt) and mutant H1t promoters in transgenic mice show that transcription of the __H1t__ gene is dependent upon the T
## Abstract The testisโspecific linker histone H1t is transcribed exclusively in pachytene spermatocytes during spermatogenesis. The H1t promoter contains two imperfect inverted repeats which together comprise the Xโbox motif that is known to bind the transcription factor regulatory factor X (RFX).