𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Transcobalamin and methionine synthase reductase mutated polymorphisms aggravate the risk of neural tube defects in humans

✍ Scribed by R.M. Guéant-Rodriguez; C. Rendeli; B. Namour; L. Venuti; A. Romano; G. Anello; P. Bosco; R. Debard; P. Gérard; M. Viola; E. Salvaggio; J.L. Guéant


Book ID
117473924
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
78 KB
Volume
344
Category
Article
ISSN
0304-3940

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Genetic polymorphisms in methylenetetrah
✍ Christensen, Benedicte; Arbour, Laura; Tran, Pamela; Leclerc, Daniel; Sabbaghian 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 47 KB 👁 2 views

Folic acid administration to women in the periconceptional period reduces the occurrence of neural tube defects (NTDs) in their offspring. A polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), 677C¨T, is the first genetic risk factor for NTDs in man identified at the molec

Thymidylate synthase repeat polymorphism
✍ Craig S. Wilding; Caroline L. Relton; Matthew J. Sutton; Pat A. Jonas; Sally-Ann 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 66 KB 👁 3 views

## Abstract ## BACKGROUND A 28‐bp repeat polymorphism in the 5′UTR of the thymidylate synthase (__TYMS__) gene represents a candidate risk factor for neural tube defects (NTDs) due to involvement in folate‐dependent homocysteine metabolism. Non‐Hispanic, white, U.S. citizens carrying at least one